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The basic principle of these methods is the placement of a barrier membrane between the soft tissue and residual bone in order to prevent the fast-proliferating epithelial cells from populating the bony defect and to provide space and time for the migration of slow-dividing osteogenic or periodontal ligament cells into the defect area.
Today, commercially available barrier membranes for GTR or GBR procedures can be divided into either non-resorbable or resorbable membranes.
Practically speaking, a barrier membrane designed for dental indications should meet the following criteria: host tissue integration, biocompatibility, cell occlusiveness, permeability for nutrients and ease of use (Hardwick et al.
Similarly, barrier membranes with intermediate barrier times, such as collprotect(r) membrane, are also adequate for the treatment of periodontal bone defects.
Periodontal regeneration following treatment with barrier membranes
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